The G protein-coupled receptors handbook / edited by Lakshmi A. Devi ; foreword by Andreas Engel, Krzysztof Palczewski.

Published
  • Totowa, N.J. : Humana Press ©2005
Physical description
1 online resource (xv, 412 pages) : illustrations
ISBN
  • 9781592599196
  • 1592599192
Local notes
Notes
  • Includes bibliographical references and index.
Contents
  • GPCRs: Structure and Function -- Structure--Function Relationships in G Protein-Coupled Receptors -- Molecular Mechanisms Involved in the Activation of Rhodopsin-Like Seven-Transmembrane Receptors -- GPCR Folding and Maturation -- Regulated Membrane Trafficking and Proteolysis of GPCRs -- GPCR Activity and Its Regulators -- Heterotrimeric G Proteins and Their Effector Pathways -- RGS Proteins -- G Protein-Coupled Receptor Kinases -- Regulators of GPCR Activity -- GPCR Interacting Proteins -- GPCR Dimerization/Oligomerization -- Biophysical and Biochemical Methods to Study GPCR Oligomerization -- Oligomerization Domains of G Protein-Coupled Receptors -- Functional Complementation and the Analysis of GPCR Dimerization -- The Role of Oligomerization in G Protein-Coupled Receptor Maturation -- Receptor Oligomerization and Trafficking -- Modulation of Receptor Pharmacology by G Protein-Coupled Receptor Dimerization -- Recent Developments in Drug Discovery -- Role of Heteromeric GPCR Interactions in Pain/Analgesia -- Conformational Plasticity of GPCR Binding Sites -- De-Orphanizing GPCRs and Drug Development.
Other names
Related item
Genre
  • Bibliography
  • Handbook
  • Handbooks and manuals.
  • Illustrated
  • text
Language
  • English

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