- 4th ed.
- Hoboken, NJ : John Wiley & Sons c2011
- Previous ed.: 2004.
- Includes bibliographical references and index.
- Guide to media resources -- Part I: Introduction and background. Life ; Aqueous solutions ; Thermodynamic principles : a review -- Part II: Biomolecules. Amino acids ; Nucleic acids, gene expression, and recombinant DNA technology ; Techniques of protein and nucleic acid purifications ; Covalent structures of proteins and nucleic acids ; Three-dimensional structures of proteins ; Protein folding, dynamics, and structural evolution ; Hemoglobin : protein function in microcosm ; Sugars and polysaccharides ; Lipids and membranes -- Part III: Mechanisms of enzyme action. Introduction to enzymes ; Rates of enzymatic reactions ; Enzymatic catalysis -- Part IV: Metabolism. Introduction to metabolism ; Glycolysis ; Glycogen metabolism ; Signal transduction ; Transport through membranes ; Citric acid cycle ; Electron transport and oxidative phosphorylation ; Other pathways of carbohydrate metabolism ; Photosynthesis ; Lipid metabolism ; Amino acid metabolism ; Energy metabolism : integration and organ specialization ; Nucleotide metabolism -- Part V: Expression and transmission of genetic information. Nucleic acid structures ; DNA replication, repair, and recombination ; Transcription ; Translation ; Viruses : paradigms for cellular function ; Eukaryotic gene expression ; Molecular physiology.
- This text explains biochemical concepts while offering a unified presentation of life and its variation through evolution. It incorporates classical and current research to illustrate the historical source of much of our biochemical knowledge.
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